Hydrea is a cancer drug for treatment of certain types of cancer or sickled red blood cells. Save money on your cancer medications and buy Generic Hydrea.

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Hydroxyurea (Hydrea) is used alone or with other medications or radiation therapy to treat a certain type of chronic myelogenous leukemia (CML; a type of cancer of the white blood cells) and certain types of head and neck cancer (including cancer of the mouth, cheek, tongue, throat, tonsils, and sinuses).

Hydroxyurea ( sold under the brand name Hydrea®) is a chemo drug that has helped some patients with CMML live longer. This drug comes as a capsule that’s taken by mouth daily. It can bring the numbers of white blood cells and monocytes down to normal.

Hydrea (Hydroxyurea) in Cancer Treatment: A Comprehensive Guide

Cancer is a formidable adversary, impacting millions of lives worldwide. The quest for effective treatments has led to the exploration of various therapeutic options. Hydrea (generic name: Hydroxyurea) is one such medication that has found utility in cancer treatment. In this comprehensive guide, we will delve into the uses, mechanisms, benefits, and potential side effects of Hydrea in the context of cancer treatment.

Understanding Hydrea:

Hydrea is a medication that belongs to the class of drugs known as antimetabolites. Originally developed for its antineoplastic (anti-cancer) properties, it has also been utilized for its ability to affect blood cell production. Hydrea’s mechanism of action involves interfering with DNA synthesis, thereby inhibiting the proliferation of rapidly dividing cells, including cancer cells.

Hydrea in Cancer Treatment:

Hydrea has demonstrated effectiveness in the treatment of several types of cancer and related conditions:

  1. Myeloproliferative Disorders: Hydrea is often used to manage myeloproliferative disorders, a group of conditions characterized by the excessive production of blood cells, including essential thrombocythemia and polycythemia vera.
  2. Sickle Cell Disease: Hydrea is employed in the treatment of sickle cell disease to reduce the frequency of pain crises and other complications.
  3. Solid Tumors: In some cases, Hydrea may be considered as part of combination chemotherapy regimens for solid tumors like melanoma, ovarian cancer, and head and neck cancers.

Mechanism of Action:

Hydrea’s primary mechanism of action involves inhibiting an enzyme called ribonucleotide reductase, which plays a crucial role in DNA synthesis. By doing so, it disrupts the production of nucleotide building blocks required for DNA replication and repair. This interference impedes the growth and division of cancer cells.

Benefits of Hydrea in Cancer Treatment:

  1. Cytoreduction: Hydrea can help reduce the excess production of blood cells in myeloproliferative disorders.
  2. Pain Management: In sickle cell disease, Hydrea can reduce pain crises and other complications.
  3. Combination Therapy: Hydrea is often used as part of combination chemotherapy regimens, enhancing the effectiveness of other anti-cancer drugs.

Treatment Process:

The administration of Hydrea varies depending on the specific condition being treated and individual patient factors. It is available in both oral tablet and capsule forms and is typically taken daily or as prescribed by a healthcare professional.

Potential Side Effects:

As with many chemotherapy drugs, Hydrea can cause side effects, including:

  • Bone Marrow Suppression: Reduced blood cell counts can lead to anemia, increased infection risk, and bleeding tendencies.
  • Nausea and Vomiting: Gastrointestinal symptoms are common but can often be managed with medications.
  • Skin Changes: Hydrea can cause changes in skin pigmentation, including darkening or reddening of the skin.
  • Mucositis: Inflammation of the mucous membranes, leading to mouth sores, can occur.
  • Gastrointestinal Effects: Diarrhea and stomach discomfort are possible side effects.

Precautions and Considerations:

It is essential for individuals considering Hydrea treatment to work closely with an oncologist or hematologist. Careful monitoring of blood counts and potential side effects is crucial to managing treatment effectively.


Hydrea (Hydroxyurea) is a medication that has demonstrated its utility in various aspects of cancer care, particularly in the treatment of myeloproliferative disorders and sickle cell disease. While its side effects can be significant, its potential benefits in managing these conditions and certain solid tumors underscore its importance in the field of oncology. Patients considering Hydrea as part of their treatment should consult with healthcare professionals to ensure it is an appropriate option for their specific circumstances.